Metanase

Description

Metanase 120 metered Nasal Spray

Indications
Mometasone Furoate nasal spray is indicated for the treatment of nasal symptoms of allergic rhinitis in patients 2 years of age and older. It is indicated for the treatment of nasal congestion associated with seasonal allergic rhinitis in patients 2 years of age and older. It is indicated for the prophylaxis of seasonal allergic rhinitis in patients 12 years of age and older. It is also indicated for the treatment of nasal polyps in patients 18 years of age and older.

Pharmacology
Mometasone Furoate is a corticosteroid with anti-inflammatory activity. The precise mechanism of corticosteroid action on allergic rhinitis is not known. Corticosteroids have been shown to have a wide range of effects on multiple cell types (e.g., mast cells, eosinophils, neutrophils, macrophages, and lymphocytes) and mediators (e.g., histamine, eicosanoids, leukotrienes, and cytokines) involved in inflammation.

Dosage
Allergic Rhinitis-
Adults and Children 12 Years of Age and Older: The recommended dose for prophylaxis and treatment of the nasal symptoms of seasonal allergic rhinitis and treatment of the nasal symptoms of perennial allergic rhinitis is two sprays (50 mcg of Mometasone Furoate in each spray) in each nostril once daily (total daily dose of 100 mcg). In patients with a known seasonal allergen that precipitates nasal symptoms of seasonal allergic rhinitis, prophylaxis with Mometasone Nasal Spray, 50 mcg (200 mcg/day) isrecommended 2 to 4 weeks prior to the anticipated start of the pollen season.
Children 2 to 11 Years of Age: The recommended dose fortreatment ofthe nasalsymptoms of seasonal and perennial allergic rhinitis is one spray (50 mcg of Mometasone Furoate in each spray) in each nostril once daily (total daily dose of 100 mcg).
Nasal Polyps Adults-
18 years of Age and Older: The recommended dose for nasal polyps is two sprays (50 mcg of Mometasone Furoate in each spray) in each nostril twice daily (total daily dose of 400 mcg). A dose of two sprays (50 mcg of mometasone furoate in each spray) in each nostril once daily (total daily dose of 200 mcg) is also effective in some patients.